Nitrate-Reducing Oral Bacteria Study
This is one of the first studies to directly test the hypothesis of a priori–identified nitrate‐reducing oral bacteria affecting cardiometabolic outcomes. Our results support the hypothesis that oral nitrate‐reducing bacteria play a beneficial role in BP regulation and insulin resistance. Future longitudinal studies with enhanced assessment of nitrate‐reducing bacterial exposure predicting progression of cardiometabolic risk biomarkers and incident clinical disease will improve temporal inference necessary to inform causality and inform the development of future intervention studies that could manipulate oral nitrate‐reducing capacity.